AFT1 anticorps (Middle Region)

N° du produit ABIN2777262

Cet anticorps Lapin Polyclonal détecte spécifiquement AFT1 dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye et Poisson zèbre (Danio rerio).

Aperçu rapide pour AFT1 anticorps (Middle Region) (ABIN2777262)

Antigène: AFT1 (Activating Transcription Factor 1 (AFT1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AFT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-AFT1 anticorps

Épitope: Middle Region

Séquence: YQIRTTPSAT SLPQTVVMTS PVTLTSQTTK TDDPQLKREI RLMKNREAAR

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%

Attributs du produit: This is a rabbit polyclonal antibody against ATF1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ATF1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 271 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur AFT1

Antigène: AFT1 (Activating Transcription Factor 1 (AFT1))

Autre désignation: ATF1

Sujet: ATF1 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT [AC] [AG]-3'), a sequence present in many viral and cellular promoters. ATF1 binds to the Tax-responsive element (TRE) of HTLV-I. ATF1 mediates PKA-induced stimulation of CRE-reporter genes.
Alias Symbols: EWS-ATF1, FUS/ATF-1, TREB36
Protein Interaction Partner: UBC, SRA1, FOSL2, GABPB1, GABPA, EDF1, HNF1B, RPS6KA5, CAMK1, RPS6KA4, CAMK2G, PRKACA, CREBBP, SPI1, JUN, CREM, CREB1, ATF1, CSNK2A2, CSNK2A1, BRCA1, CSNK2B, CAMK2A, FOSL1,
Protein Size: 271

Poids moléculaire: 29 kDa

ID gène: 466

NCBI Accession: NM_005171, NP_005162

UniProt: P18846

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades