KLF8 anticorps (N-Term)

N° du produit ABIN2777342

Détail du produit anti-KLF8 anticorps

Antigène: KLF8 (Kruppel-Like Factor 8 (KLF8))

Épitope: N-Term

Reactivité: Humain, Lapin, Chien, Cheval, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLF8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: LSFHKPKAPL QPASMLQAPI RPPKPQSSPQ TLVVSTSTSD MSTSANIPTV

Homologie: Cow: 79%, Dog: 79%, Horse: 77%, Human: 100%, Rabbit: 86%

Attributs du produit: This is a rabbit polyclonal antibody against KLF8. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human KLF8

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 359 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-KLF8 (ABIN2777342)

Yan, Zhang, Wu, Wu, Zhang, Shi, Zhao, Nan, Chen, Wang, Cheng, Li, Bai, Liu, Wang: "KLF8 promotes tumorigenesis, invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2." dans: Oncotarget, Vol. 6, Issue 28, pp. 25402-17, (2015) (PubMed).

Han, Han, Sun, Zan, Zhou, Xu, Yao, Liu: "Krüppel?like factor expression and correlation with FAK, MMP?9 and E?cadherin expression in hepatocellular carcinoma." dans: Molecular medicine reports, Vol. 8, Issue 1, pp. 81-8, (2013) (PubMed).

Fu, Li, Wu, Yang, Mo, Huang, Xia, Ding, Liu, Zhu: "Small interference RNA targeting Krüppel-like factor 8 inhibits the renal carcinoma 786-0 cells growth in vitro and in vivo." dans: Journal of cancer research and clinical oncology, Vol. 136, Issue 8, pp. 1255-65, (2010) (PubMed).

Li, Yang, Sun, Xu, Zhou, Qiu, Ke, Cui, Wang, Wang, Liu, Fan: "Up-regulation of Krüppel-like factor 8 promotes tumor invasion and indicates poor prognosis for hepatocellular carcinoma." dans: Gastroenterology, Vol. 139, Issue 6, pp. 2146-2157.e12, (2010) (PubMed).

Détails sur KLF8

Antigène: KLF8 (Kruppel-Like Factor 8 (KLF8))

Autre désignation: KLF8 (KLF8 Produits)

Synonymes: anticorps klf8, anticorps BKLF3, anticorps ZNF741, anticorps A830097P10Rik, anticorps ZNF74, anticorps Klf8-ps1, anticorps RGD1565831, anticorps Kruppel like factor 8, anticorps Kruppel-like factor 8, anticorps KLF8, anticorps klf8, anticorps Klf8

Sujet: KLF8 is abnormally expressed in female patients with X autosome translocation t(X,21)(p11.2,q22.3) and non-syndromic mental retardation.
Alias Symbols: BKLF3, DKFZp686O08126, DXS741, MGC138314, ZNF741
Protein Interaction Partner: Dlg4, APP, UBC, XPO1, PARP1, KAT2B, EP300, CREBBP, FHL3, CTBP2,
Protein Size: 359

Poids moléculaire: 39 kDa

ID gène: 11279

NCBI Accession: NM_007250, NP_009181

UniProt: O95600