FGD1 anticorps (C-Term)

N° du produit ABIN2777407

Cet anticorps anti-FGD1 Polyclonal Lapin (ABIN2777407) détecte spécifiquement FGD1 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Boeuf (Vache), Chien, Souris, Porc, Rat, Lapin et Cheval.

Aperçu rapide pour FGD1 anticorps (C-Term) (ABIN2777407)

Antigène: FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))

Reactivité: Humain, Boeuf (Vache), Chien, Souris, Porc, Rat, Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGD1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-FGD1 anticorps

Épitope: C-Term

Fonction: FGD1 Antibody - C-terminal region

Séquence: WMAVLGRAGR GDTFCPGPTL SEDREMEEAP VAALGATAEP PESPQTRDKT

Homologie: Cow: 86%, Dog: 86%, Horse: 79%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 79%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against FGD1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human FGD1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8101064

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur FGD1

Antigène: FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))

Autre désignation: FGD1

Sujet:

Background Information: FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.

Gene Name: FYVE, RhoGEF and PH domain containing 1

Alternative Symbols: AAS, FGDY, MRXS16, ZFYVE3

Protein Name: FYVE, RhoGEF and PH domain-containing protein 1

Poids moléculaire: 107kDa

ID gène: 2245

NCBI Accession: NP_004454

UniProt: P98174

Pathways: Neurotrophin Signaling Pathway