FGD1 anticorps (C-Term)

N° du produit ABIN2777407

Détail du produit anti-FGD1 anticorps

Antigène: FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))

Épitope: C-Term

Reactivité: Humain, Boeuf (Vache), Porc, Rat, Chien, Lapin, Souris, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGD1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: WMAVLGRAGR GDTFCPGPTL SEDREMEEAP VAALGATAEP PESPQTRDKT

Homologie: Cow: 86%, Dog: 86%, Horse: 79%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 79%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against FGD1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human FGD1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 961 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FGD1

Antigène: FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))

Autre désignation: FGD1 (FGD1 Produits)

Synonymes: anticorps AAS, anticorps FGDY, anticorps MRXS16, anticorps ZFYVE3, anticorps FYVE, RhoGEF and PH domain containing 1, anticorps FGD1, anticorps Fgd1, anticorps fgd1

Sujet: FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.
Alias Symbols: AAS, FGDY, MRXS16, ZFYVE3
Protein Interaction Partner: BTRC, UBC, ELAVL1, ELMO1, CTTN, CDC42, AOC1,
Protein Size: 961

Poids moléculaire: 107 kDa

ID gène: 2245

NCBI Accession: NM_004463, NP_004454

UniProt: P98174

Pathways: Neurotrophin Signaling Pathway