TLR6 anticorps (Middle Region)
Aperçu rapide pour TLR6 anticorps (Middle Region) (ABIN2777430)
Antigène
Voir toutes TLR6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- Middle Region
-
Séquence
- KCLVRVFQFL WPKPVEYLNI YNLTIIESIR EEDFTYSKTT LKALTIEHIT
-
Homologie
- Goat: 85%, Human: 100%, Sheep: 86%
-
Attributs du produit
- This is a rabbit polyclonal antibody against TLR6. It was validated on Western Blot and immunohistochemistry.
-
Purification
- Affinity Purified
-
Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human TLR6
-
-
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
-
Commentaires
-
Antigen size: 480 AA
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- TLR6 (Toll-Like Receptor 6 (TLR6))
-
Autre désignation
- TLR6
-
Sujet
-
TLR6 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins.
Alias Symbols: CD286
Protein Interaction Partner: BTK, TRAP1, TLR2,
Protein Size: 480 -
Poids moléculaire
- 53 kDa
-
ID gène
- 10333
-
NCBI Accession
- NM_006068
-
UniProt
- Q2NKL3
-
Pathways
- Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
Antigène
-