TOLLIP anticorps (C-Term)

N° du produit ABIN2777431

Cet anticorps Lapin Polyclonal détecte spécifiquement TOLLIP dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye, Cheval, Lapin et Saccharomyces cerevisiae.Il a été cité dans 1 publication.

Aperçu rapide pour TOLLIP anticorps (C-Term) (ABIN2777431)

Antigène: TOLLIP (Toll Interacting Protein (TOLLIP))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye, Cheval, Lapin, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TOLLIP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TOLLIP anticorps

Épitope: C-Term

Séquence: MATTVSTQRG PVYIGELPQD FLRITPTQQQ RQVQLDAQAA QQLQYGGAVG

Homologie: Cow: 85%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 83%, Rat: 100%, Yeast: 79%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TOLLIP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human TOLLIP

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 274 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TOLLIP (ABIN2777431)

Schimming, Parwez, Petrasch-Parwez, Nothnagel, Epplen, Hoffjan: "Association of toll-interacting protein gene polymorphisms with atopic dermatitis." dans: BMC dermatology, Vol. 7, pp. 3, (2007) (PubMed).

Détails sur TOLLIP

Antigène: TOLLIP (Toll Interacting Protein (TOLLIP))

Autre désignation: TOLLIP

Sujet: TOLLIP is component of the signaling pathway of IL-1 and Toll-like receptors. It Inhibits cell activation by microbial products. It also recruits IRAK1 to the IL-1 receptor complex and inhibits IRAK1 phosphorylation and kinase activity.
Alias Symbols: FLJ33531, IL-1RAcPIP
Protein Interaction Partner: RBPMS, TOM1, DAZAP2, UBC, SIAH1, PRR20A, WDYHV1, CPSF6, DAB1, ATG8, MAP1LC3A, SQSTM1, NBR1, VPS35, OXR1, VPS29, CYHR1, NMI, APEH, RHOXF2, TOM1L1, IRAK1, PINK1, INTS4P2, SNX8, TRIP6, UBD, TGFBR1, ATXN1, SMAD7, TOM1L2, TOLLIP, GGA1, GGA3, GGA2, TRAF6, RAC1,
Protein Size: 274

Poids moléculaire: 30 kDa

ID gène: 54472

NCBI Accession: NM_019009, NP_061882

UniProt: Q9H0E2