HES1 anticorps (C-Term)

N° du produit ABIN2777527

Détail du produit anti-HES1 anticorps

Antigène: HES1 (Hes Family bHLH Transcription Factor 1 (HES1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HES1 est non-conjugé

Application: Western Blotting (WB)

Séquence: AFLIPNGAFA HSGPVIPVYT SNSGTSVGPN AVSPSSGSSL TADSMWRPWR

Homologie: Cow: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Hes1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide corresponding to a region of Rat

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 281 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HES1

Antigène: HES1 (Hes Family bHLH Transcription Factor 1 (HES1))

Autre désignation: Hes1 (HES1 Produits)

Synonymes: anticorps HES-1, anticorps HHL, anticorps HRY, anticorps bHLHb39, anticorps Hry, anticorps HAIRY1, anticorps c-hairy1A, anticorps Xhairy1, anticorps hairy1, anticorps hes1, anticorps Xhairy-1, anticorps Xlh1, anticorps hes family bHLH transcription factor 1, anticorps hairy and enhancer of split 1 (Drosophila), anticorps hes family bHLH transcription factor 4, anticorps hes family bHLH transcription factor 1 S homeolog, anticorps hes family bHLH transcription factor 1 L homeolog, anticorps HES1, anticorps Hes1, anticorps HES4, anticorps hes1.S, anticorps hes1.L

Sujet: Hes1 is the transcriptional repressor of genes that require a bHLH protein for their transcription. Hes1 may act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Hes1 binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity.
Alias Symbols: Hes1
Protein Interaction Partner: Polr2a, Kat2b, Sfpq, Src, Crebbp, Parp1, Camk2a,
Protein Size: 281

Poids moléculaire: 30 kDa

ID gène: 29577

NCBI Accession: NM_024360, NP_077336

UniProt: Q04666

Pathways: Réparation de l'ADN