ME1 anticorps (N-Term)

N° du produit ABIN2777597

Cet anticorps anti-ME1 est un anticorps Lapin Polyclonal détectant ME1 dans WB et IHC. Adapté pour Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cheval, Mouton et Porc.

Aperçu rapide pour ME1 anticorps (N-Term) (ABIN2777597)

Antigène: ME1 (Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cheval, Mouton, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ME1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-ME1 anticorps

Épitope: N-Term

Séquence: QQLNIHGLLP PSFNSQEIQV LRVVKNFEHL NSDFDRYLLL MDLQDRNEKL

Homologie: Cow: 92%, Dog: 85%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 91%, Rabbit: 100%, Rat: 100%, Sheep: 92%

Attributs du produit: This is a rabbit polyclonal antibody against ME1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ME1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 572 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ME1

Antigène: ME1 (Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))

Autre désignation: ME1

Sujet: ME1 is a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HUMNDME, MES
Protein Interaction Partner: UBC, VTA1, RPUSD2, GORASP2, BOP1, TOM1, NMI, CUL3, UGDH, TBCD, GTF2A1, GARS, CTTN,
Protein Size: 572

Poids moléculaire: 64 kDa

ID gène: 4199

NCBI Accession: NM_002395, NP_002386

UniProt: P48163

Pathways: Regulation of Lipid Metabolism by PPARalpha