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ME1 anticorps (N-Term)

Cet anticorps anti-ME1 Polyclonal Lapin (ABIN2777597) détecte spécifiquement ME1 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Lapin, Cheval, Porc, Mouton et Boeuf (Vache).
N° du produit ABIN2777597
534,11 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 6 à 9 jours ouvrables

Aperçu rapide pour ME1 anticorps (N-Term) (ABIN2777597)

Antigène

Voir toutes ME1 Anticorps
ME1 (Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))

Reactivité

  • 67
  • 36
  • 35
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat, Chien, Lapin, Cheval, Porc, Mouton, Boeuf (Vache)

Hôte

  • 50
  • 18
Lapin

Clonalité

  • 50
  • 18
Polyclonal

Conjugué

  • 38
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp ME1 est non-conjugé

Application

  • 40
  • 20
  • 19
  • 14
  • 10
  • 9
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Épitope

    • 29
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Fonction

    ME1 Antibody - N-terminal region

    Séquence

    QQLNIHGLLP PSFNSQEIQV LRVVKNFEHL NSDFDRYLLL MDLQDRNEKL

    Homologie

    Cow: 92%, Dog: 85%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 91%, Rabbit: 100%, Rat: 100%, Sheep: 92%

    Attributs du produit

    This is a rabbit polyclonal antibody against ME1. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the N terminal region of human ME1
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Commentaires

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8104821

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.5 mg/mL

    Buffer

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    prevent freeze-thaw cycles

    Stock

    4 °C,-20 °C

    Stockage commentaire

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    ME1 (Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))

    Autre désignation

    ME1

    Sujet

    Background Information: ME1 is a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Gene Name: Malic enzyme 1, NADP(+)-dependent, cytosolic

    Alternative Symbols: MES, HUMNDME

    Protein Name: NADP-dependent malic enzyme

    Poids moléculaire

    64kDa

    ID gène

    4199

    NCBI Accession

    NP_002386

    UniProt

    P48163

    Pathways

    Regulation of Lipid Metabolism by PPARalpha
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