COPS5 anticorps (N-Term)

N° du produit ABIN2777618

Cet anticorps anti-COPS5 Polyclonal Lapin (ABIN2777618) détecte spécifiquement COPS5 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour COPS5 anticorps (N-Term) (ABIN2777618)

Antigène: COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COPS5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-COPS5 anticorps

Épitope: N-Term

Fonction: COPS5 Antibody - N-terminal region

Séquence: NMQEAQSIDE IYKYDKKQQQ EILAAKPWTK DHHYFKYCKI SALALLKMVM

Attributs du produit: This is a rabbit polyclonal antibody against COPS5. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human COPS5

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32834-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur COPS5

Antigène: COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))

Autre désignation: COPS5

Sujet:

Targeted Subunit: 5

Background Information: The protein encoded by COPS5 is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors.

Gene Name: COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)

Alternative Symbols: CSN5, JAB1, SGN5, MOV-34

Protein Name: COP9 signalosome complex subunit 5

Poids moléculaire: 38kDa

ID gène: 10987

NCBI Accession: NP_006828

UniProt: Q92905

Pathways: Cycle Cellulaire