DMAP1 anticorps (N-Term)

N° du produit ABIN2777663

Cet anticorps Lapin Polyclonal détecte spécifiquement DMAP1 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Lapin, Poisson zèbre (Danio rerio) et Cheval.

Aperçu rapide pour DMAP1 anticorps (N-Term) (ABIN2777663)

Antigène: DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Lapin, Poisson zèbre (Danio rerio), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DMAP1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DMAP1 anticorps

Épitope: N-Term

Fonction: DMAP1 Antibody - N-terminal region

Séquence: DAWTKAETDH LFDLSRRFDL RFVVIHDRYD HQQFKKRSVE DLKERYYHIC

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against DMAP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DMAP1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8099054

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur DMAP1

Antigène: DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

Autre désignation: DMAP1

Sujet:

Background Information: DMAP1 is a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.

Gene Name: DNA methyltransferase 1 associated protein 1

Alternative Symbols: EAF2, SWC4, MEAF2, DNMAP1, DNMTAP1

Protein Name: DNA methyltransferase 1-associated protein 1

Poids moléculaire: 51kDa

ID gène: 55929

NCBI Accession: NP_001029196

UniProt: Q9NPF5