PIAS4 anticorps (N-Term)

N° du produit ABIN2777708

Cité dans 1 publication. Cet anticorps anti-PIAS4 Polyclonal Lapin (ABIN2777708) détecte spécifiquement PIAS4 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval et Poisson zèbre (Danio rerio).

Aperçu rapide pour PIAS4 anticorps (N-Term) (ABIN2777708)

Antigène: PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIAS4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PIAS4 anticorps

Épitope: N-Term

Fonction: PIAS4 Antibody - N-terminal region

Séquence: AKNMVMSFRV SDLQMLLGFV GRSKSGLKHE LVTRALQLVQ FDCSPELFKK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against PIAS4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PIAS4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8109285

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PIAS4 (ABIN2777708)

Zhang, Xu, Han, Wei, Shu: "PIASy represses TRIF-induced ISRE and NF-kappaB activation but not apoptosis." dans: FEBS letters, Vol. 570, Issue 1-3, pp. 97-101, (2004) (PubMed).

Détails sur PIAS4

Antigène: PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))

Autre désignation: PIAS4

Sujet:

Background Information: PIAS4 is an inhibitor of TRIF-induced ISRE and NF-kappaB activation. Its mRNA is selectively expressed in endothelial cells, and its expression can be regulated by angiogenic growth factors

Gene Name: Protein inhibitor of activated STAT, 4

Alternative Symbols: PIASY, Piasg, ZMIZ6, PIAS-gamma

Protein Name: E3 SUMO-protein ligase PIAS4

Poids moléculaire: 57kDa

ID gène: 51588

NCBI Accession: NP_056981

UniProt: Q8N2W9

Pathways: Signalistation JAK/STAT, Interferon-gamma Pathway, Positive Regulation of Response to DNA Damage Stimulus