SUFUH anticorps (Middle Region)

N° du produit ABIN2777710

Cet anticorps Lapin Polyclonal détecte spécifiquement SUFUH dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio) et Boeuf (Vache).

Aperçu rapide pour SUFUH anticorps (Middle Region) (ABIN2777710)

Antigène: SUFUH (Suppressor of Fused Homolog (SUFUH))

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUFUH est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SUFUH anticorps

Épitope: Middle Region

Séquence: NGQGILELLR TVPIAGGPWL ITDMRRGETI FEIDPHLQER VDKGIETDGS

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SUFU. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SUFU

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 484 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SUFUH

Antigène: SUFUH (Suppressor of Fused Homolog (SUFUH))

Autre désignation: SUFU

Sujet: SUFU is a component of the Sonic hedgehog (SHH, MIM 600725)/Patched (PTCH, MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes. SUFU encodes a component of the sonic hedgehog (SHH, MIM 600725)/patched (PTCH, MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945, BCNS, MIM 109400, and GCPS, MIM 175700).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PRO1280, SUFUH, SUFUXL
Protein Interaction Partner: ZNF747, FBXL17, GLIS3, UBC, GLI1, HDX, SAP18, RCN3, PIAS1, PEX26, ZNF764, STK36, ZNF446, QPRT, SETDB1, MID1IP1, RNF19A, SUFU, ZNF219, ZNF263, BTRC, LAMTOR3, NCOA3, HMGA1, GLI3, GLI2, HNRNPA1, LGALS3, RBPJ,
Protein Size: 484

Poids moléculaire: 54 kDa

ID gène: 51684

NCBI Accession: NM_016169, NP_057253

UniProt: Q9UMX1

Pathways: Signalisation Hedgehog, Tube Formation, Maintenance of Protein Location