HSP70 1A anticorps (Middle Region)
Aperçu rapide pour HSP70 1A anticorps (Middle Region) (ABIN2777745)
Antigène
Voir toutes HSP70 1A (HSPA1A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- SLFEGIDFYT SITRARFEEL CSDLFRSTLE PVEKALRDAK LDKAQIHDLV
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Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against HSPA1A. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Protein A purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human HSPA1A
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 476 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Genomic consequences of cytochrome P450 2C9 overexpression in human hepatoma cells." dans: Chemical research in toxicology, Vol. 22, Issue 5, pp. 779-87, (2009) (PubMed).
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: "Genomic consequences of cytochrome P450 2C9 overexpression in human hepatoma cells." dans: Chemical research in toxicology, Vol. 22, Issue 5, pp. 779-87, (2009) (PubMed).
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- HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))
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Autre désignation
- HSPA1A
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Sujet
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HSPA1A is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1.
Alias Symbols: HSP72, HSPA1, HSP70I, HSPA1B, HSP70-1, HSP70-1A
Protein Interaction Partner: UBC, TP53, NEDD1, HAUS1, CEP76, CEP72, HAUS2, AIRE, CEP250, TUBGCP2, TUBGCP3, SAE1, CEP57, AURKB, TUBG1, AURKA, SUMO2, TUBGCP4, PPP2R1A, LGALS3BP, EMD, CDKN1A, CDC20, SUMO3, STAU1, MDM2, TRIM25, ASB10, ASB16, WWOX, EZH2, BMI1, SUZ12, TUBA4A, EIF6, ALDOC,
Protein Size: 476 -
Poids moléculaire
- 52 kDa
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ID gène
- 3303
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NCBI Accession
- NM_005345
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UniProt
- P08107
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Antigène
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