PURA anticorps (Middle Region)

N° du produit ABIN2777802

Cet anticorps Lapin Polyclonal détecte spécifiquement PURA dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Mouton et Cobaye.

Aperçu rapide pour PURA anticorps (Middle Region) (ABIN2777802)

Antigène: PURA (Purine-Rich Element Binding Protein A (PURA))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Mouton, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PURA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-PURA anticorps

Épitope: Middle Region

Séquence: VEFRDYLGDF IEHYAQLGPS QPPDLAQAQD EPRRALKSEF LVRENRKYYM

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PURA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PURA

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 322 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PURA

Antigène: PURA (Purine-Rich Element Binding Protein A (PURA))

Autre désignation: PURA

Sujet: PURA is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PUR-ALPHA, PUR1, PURALPHA
Protein Interaction Partner: RAF1, UBC, LIN28B, LIN28A, BMI1, TARDBP, IGSF8, ICAM1, IL7R, ZNF638, DDX23, RFC3, RFC2, RB1, PURB, POLA1, CAND1, CUL1, CUL3, EIF2AK2, POU5F1, MEPCE, HNRNPA1, ADAP1, CCNT1, E2F1, SP1, YBX1, CDK5, CNBP, Jvgp5,
Protein Size: 322

Poids moléculaire: 35 kDa

ID gène: 5813

NCBI Accession: NM_005859, NP_005850

UniProt: Q00577