PRDM12 anticorps (N-Term)

N° du produit ABIN2777809

Cet anticorps Lapin Polyclonal détecte spécifiquement PRDM12 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Porc et Cobaye.

Aperçu rapide pour PRDM12 anticorps (N-Term) (ABIN2777809)

Antigène: PRDM12 (PR Domain Containing 12 (PRDM12))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Porc, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRDM12 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PRDM12 anticorps

Épitope: N-Term

Fonction: PRDM12 Antibody - N-terminal region

Séquence: SFLYGRWRNV LGEQLFEDKS HHASPKTAFT AEVLAQSFSG EVQKLSSLVL

Homologie: Cow: 100%, Dog: 91%, Guinea Pig: 92%, Human: 100%, Mouse: 92%, Pig: 100%, Rat: 92%, Zebrafish: 83%

Attributs du produit: This is a rabbit polyclonal antibody against PRDM12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PRDM12

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33218-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PRDM12

Antigène: PRDM12 (PR Domain Containing 12 (PRDM12))

Autre désignation: PRDM12

Sujet:

Background Information: PRDM12 belongs to PR-domain family which are involved in human cancers in an unusual yin-yang fashion. Two products are normally produced from a PR-domain family member which differ by the presence or absence of the PR domain, the PR-plus product is disrupted or underexpressed whereas the PR-minus product is present or overexpressed in cancer cells. This imbalance in the amount of the two products, a result of either genetic or epigenetic events, appears to be an important cause of malignancy. PRDM12 may have a potential role in the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion.

Gene Name: PR domain containing 12

Alternative Symbols: PFM9, HSAN8

Protein Name: PR domain zinc finger protein 12

Poids moléculaire: 40kDa

ID gène: 59335

NCBI Accession: NP_067632

UniProt: Q9H4Q4