RORC anticorps (Middle Region)

N° du produit ABIN2777822

Il existe 1 publication pour ce produit. L’anticorps anti-RORC Polyclonal Lapin est utilisé pour la détection de RORC dans des échantillons de Humain, Souris, Rat, Cheval, Boeuf (Vache), Lapin et Porc. Il a été validé pour WB.

Aperçu rapide pour RORC anticorps (Middle Region) (ABIN2777822)

Antigène: RORC (RAR-Related Orphan Receptor C (RORC))

Reactivité: Humain, Souris, Rat, Cheval, Boeuf (Vache), Lapin, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RORC est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RORC anticorps

Épitope: Middle Region

Fonction: RORC Antibody - middle region

Séquence: CHLEYSPERG KAEGRESFYS TGSQLTPDRC GLRFEEHRHP GLGELGQGPD

Homologie: Cow: 92%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 79%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against RORC. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human RORC

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33243-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-RORC (ABIN2777822)

Huang, Huang, Lee, Ng, Chang: "Postirradiation sinus mucosa disease in nasopharyngeal carcinoma patients." dans: The Laryngoscope, Vol. 117, Issue 4, pp. 737-42, (2007) (PubMed).

Détails sur RORC

Antigène: RORC (RAR-Related Orphan Receptor C (RORC))

Autre désignation: RORC

Sujet:

Background Information: RORC encodes a protein which is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that RORC may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2.The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: RAR-related orphan receptor C

Alternative Symbols: TOR, RORG, RZRG, IMD42, NR1F3, RZR-GAMMA

Protein Name: cDNA FLJ40675 fis, clone THYMU2021714, highly similar to NUCLEAR RECEPTOR ROR-GAMMA EMBL BAG53561.1

Poids moléculaire: 56kDa

ID gène: 6097

NCBI Accession: NP_001001523

UniProt: B3KUU9

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway