Sp3 anticorps (Middle Region)

N° du produit ABIN2777872

Cet anticorps anti-Sp3 est un anticorps Lapin Polyclonal détectant Sp3 dans WB et IHC. Adapté pour Humain, Souris, Rat, Cobaye, Cheval, Lapin, Boeuf (Vache) et Chien.

Aperçu rapide pour Sp3 anticorps (Middle Region) (ABIN2777872)

Antigène: Sp3 (Sp3 Transcription Factor (Sp3))

Reactivité: Humain, Souris, Rat, Cobaye, Cheval, Lapin, Boeuf (Vache), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Sp3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Sp3 anticorps

Épitope: Middle Region

Séquence: TAGINADGHL INTGQAMDSS DNSERTGERV SPDINETNTD TDLFVPTSSS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SP3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SP3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 781 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Sp3

Antigène: Sp3 (Sp3 Transcription Factor (Sp3))

Autre désignation: SP3

Sujet: SP3 is a transcriptional factor that can act as an activator or repressor, probably in a isoform-specific manner. SP3 binds to GT and GC boxes promoters elements.This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted.
Alias Symbols: DKFZp686O1631, SPR-2, SPR2
Protein Interaction Partner: SP1, SUMO1, PPP2R4, PPP1CC, GCH1, HLTF, TFAP4, YY1, SUMO2, UBC, RELA, MECP2, HDAC2, HDAC1, ZBTB7B, EP300, CRX, TP53, NKX3-1, CREBBP, CEBPB, ESR1, DNMT1, SFPQ, PIAS1, GRIN1, GABPA, ZBTB7A, UBE2I, STK19, RBBP4, E2F1, RB1, SP4, TNFSF10, SENP1,
Protein Size: 781

Poids moléculaire: 82 kDa

ID gène: 6670

NCBI Accession: NM_003111, NP_003102

UniProt: Q02447