Sp3 anticorps (N-Term)

N° du produit ABIN2777873

Cet anticorps Lapin Polyclonal détecte spécifiquement Sp3 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Cobaye, Cheval, Lapin, Boeuf (Vache) et Chien.

Aperçu rapide pour Sp3 anticorps (N-Term) (ABIN2777873)

Antigène: Sp3 (Sp3 Transcription Factor (Sp3))

Reactivité: Humain, Souris, Rat, Cobaye, Cheval, Lapin, Boeuf (Vache), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Sp3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Sp3 anticorps

Épitope: N-Term

Séquence: SSSSQLPVTI DSTGILQQNT NSLTTSSGQV HSSDLQGNYI QSPVSEETQA

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SP3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SP3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Sp3

Antigène: Sp3 (Sp3 Transcription Factor (Sp3))

Autre désignation: SP3

Sujet: This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13.
Protein Interaction Partner: SP1, SUMO1, PPP2R4, PPP1CC, GCH1, HLTF, TFAP4, YY1, SUMO2, UBC, RELA, MECP2, HDAC2, HDAC1, ZBTB7B, EP300, CRX, TP53, NKX3-1, CREBBP, CEBPB, ESR1, DNMT1, SFPQ, PIAS1, GRIN1, GABPA, ZBTB7A, UBE2I, STK19, RBBP4, E2F1, RB1, SP4, TNFSF10, SENP1,
Protein Size: 479

Poids moléculaire: 52 kDa

ID gène: 6670