EPC1 anticorps (Middle Region)

N° du produit ABIN2777875

L’anticorps Lapin Polyclonal anti-EPC1 a été validé pour WB. Il convient pour détecter EPC1 dans des échantillons de Humain, Souris, Boeuf (Vache), Chien, Cheval, Lapin, Rat, Cobaye et Porc.

Aperçu rapide pour EPC1 anticorps (Middle Region) (ABIN2777875)

Antigène: EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))

Reactivité: Humain, Souris, Boeuf (Vache), Chien, Cheval, Lapin, Rat, Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPC1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-EPC1 anticorps

Épitope: Middle Region

Séquence: VNKQDKADLI RPKRKYEKKP KVLPSSAAAT PQQTSPAALP VFNAKDLNQY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against EPC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human EPC1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 836 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur EPC1

Antigène: EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))

Autre désignation: EPC1

Sujet: EPC1 is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.
Alias Symbols: DKFZp781P2312, Epl1
Protein Interaction Partner: RINT1, KRT15, Hopx, TRIM27, H2AFZ, DMAP1, ING3, MORF4L1, KAT5, MYC, MORF4L2, MRGBP, EED, EZH2, E2F6, SRF,
Protein Size: 836

Poids moléculaire: 93 kDa

ID gène: 80314

NCBI Accession: NM_025209, NP_079485

UniProt: Q9H2F5

Pathways: Regulation of Muscle Cell Differentiation