T-Box 1 anticorps (Middle Region)

N° du produit ABIN2777911

Détail du produit anti-T-Box 1 anticorps

Antigène: T-Box 1 (TBX1)

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Cobaye, Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp T-Box 1 est non-conjugé

Application: Western Blotting (WB)

Séquence: PVASPTQPSG TEKGGHVLKD KEVKAETSRN TPEREVELLR DAGGCVNLGL

Homologie: Guinea Pig: 85%, Horse: 77%, Human: 100%, Mouse: 77%, Rabbit: 85%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against TBX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TBX1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 398 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur T-Box 1

Antigène: T-Box 1 (TBX1)

Autre désignation: TBX1 (TBX1 Produits)

Synonymes: anticorps CAFS, anticorps CTHM, anticorps DGCR, anticorps DGS, anticorps DORV, anticorps TBX1C, anticorps TGA, anticorps VCFS, anticorps mp:zf637-3-000616, anticorps zgc:136724, anticorps TBX1, anticorps dgs, anticorps tga, anticorps cafs, anticorps cthm, anticorps dgcr, anticorps dorv, anticorps vcfs, anticorps tbx1c, anticorps xtbx1, anticorps tbx1, anticorps T-box 1, anticorps T-box 1 S homeolog, anticorps T-box 1 L homeolog, anticorps TBX1, anticorps Tbx1, anticorps tbx1, anticorps tbx1.S, anticorps tbx1.L

Sujet: TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. TBX1 product shares 98 % amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where TBX1 has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98 % amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: CAFS, CTHM, DGCR, DGS, DORV, TBX1C, TGA, VCFS
Protein Interaction Partner: TERF2, TERF1,
Protein Size: 398

Poids moléculaire: 43 kDa

ID gène: 6899

NCBI Accession: NM_080646, NP_542377

UniProt: O43435

Pathways: Retinoic Acid Receptor Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation