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TCF7L2 anticorps (N-Term)

TCF7L2 Reactivité: Humain, Rat, Souris, Boeuf (Vache), Poisson zèbre (Danio rerio), Porc, Cobaye WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2777926
  • Antigène Voir toutes TCF7L2 Anticorps
    TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))
    Épitope
    • 15
    • 11
    • 10
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 48
    • 29
    • 29
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Rat, Souris, Boeuf (Vache), Poisson zèbre (Danio rerio), Porc, Cobaye
    Hôte
    • 61
    • 7
    Lapin
    Clonalité
    • 52
    • 16
    Polyclonal
    Conjugué
    • 29
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TCF7L2 est non-conjugé
    Application
    • 46
    • 25
    • 18
    • 14
    • 13
    • 9
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    MPQLNGGGGD DLGANDELIS FKDEGEQEEK SSENSSAERD LADVKSSLVN
    Homologie
    Cow: 100%, Guinea Pig: 79%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 100%, Zebrafish: 93%
    Attributs du produit
    This is a rabbit polyclonal antibody against TCF7L2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human TCF7L2
    Top Product
    Discover our top product TCF7L2 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 596 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))
    Autre désignation
    TCF7L2 (TCF7L2 Produits)
    Synonymes
    anticorps TCF4B, anticorps TCF4E, anticorps Tcf-4, anticorps Tcf4, anticorps mTcf-4B, anticorps mTcf-4E, anticorps tcf4, anticorps XTCF-4, anticorps tcf4e, anticorps TCF4, anticorps TCF-4, anticorps TCFL2, anticorps transcription factor 7 like 2, anticorps transcription factor 7-like 2, anticorps transcription factor 7 like 2, T cell specific, HMG box, anticorps transcription factor 7 like 2 L homeolog, anticorps transcription factor 7-like 2 (T-cell specific, HMG-box), anticorps TCF7L2, anticorps LOC100545943, anticorps Tcf7l2, anticorps tcf7l2, anticorps tcf7l2.L
    Sujet
    The TCL7L2 is a high mobility group (HMG) box-containing transcription factor implicated in blood glucose homeostasis. The study of Yi et al. suggested that TCL7L2 acts through regulation of proglucagon through repression of the proglucagon gene in enteroendocrine cells via the Wnt signaling pathway. The TCL7L2 gene product is a high mobility group (HMG) box-containing transcription factor implicated in blood glucose homeostasis. The study of Yi et al. (2005) [PubMed 15525634] suggested that TCL7L2 acts through regulation of proglucagon (MIM 138030) through repression of the proglucagon gene in enteroendocrine cells via the Wnt signaling pathway.[supplied by OMIM]. Sequence Note: This gene (TCF7L2, alias TCF-4) is distinct from TCF4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-202 DA473655.1 1-202 203-251 Y11306.2 3-51 252-1252 AK225809.1 256-1256 1253-1305 Y11306.2 1053-1105 1306-1756 AK225809.1 1310-1760 1757-1811 Y11306.2 1557-1611 1812-2652 AK225809.1 1765-2605
    Alias Symbols: TCF-4, TCF4
    Protein Interaction Partner: UBC, FBLN1, UBE2I, PSMA3, MAD2L2, ZBTB33, DAXX, CTNNB1, ELAVL1, PARP1, XRCC5, SUMO2, XRCC6, NR5A1, EP300, CEBPA, CTBP1, DAZAP2, CTNNBIP1, JUP, CSNK2A2, CSNK2A1, PSEN1, NLK, RAC1,
    Protein Size: 596
    Poids moléculaire
    65 kDa
    ID gène
    6934
    NCBI Accession
    NM_030756, NP_110383
    UniProt
    Q6FHW4
    Pathways
    Signalisation WNT, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus
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