TSG101 anticorps (N-Term)

N° du produit ABIN2777954

Cet anticorps anti-TSG101 est un anticorps Lapin Polyclonal détectant TSG101 dans WB et IHC. Adapté pour Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cheval, Chévre, Cobaye et Poisson zèbre (Danio rerio).

Aperçu rapide pour TSG101 anticorps (N-Term) (ABIN2777954)

Antigène: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cheval, Chévre, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSG101 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-TSG101 anticorps

Épitope: N-Term

Séquence: YKYRDLTVRE TVNVITLYKD LKPVLDSYVF NDGSSRELMN LTGTIPVPYR

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against TSG101. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TSG101

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TSG101

Antigène: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Autre désignation: TSG101

Sujet: The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
Alias Symbols: TSG10, VPS23
Protein Interaction Partner: USHBP1, CEP55, VPS37C, VPS28, AATF, MGRN1, PDLIM7, TAX1BP1, KRT31, KRT13, KIFC3, DAPK3, AR, FAM9B, VPS37A, HAUS1, SYCE1, UBC, LRSAM1, ADRB2, MVB12A, UBAP1, CDKN1A, HGS, gag, gag-pol, GRB2, CDS2, ZFYVE9, VCP, VPS37B, WDR12, XPO1, UBD, ARRDC1, KCNN4, RAB11F
Protein Size: 390

Poids moléculaire: 44 kDa

ID gène: 7251

NCBI Accession: NM_006292, NP_006283

UniProt: Q99816