TUB anticorps (N-Term)

N° du produit ABIN2777955

Cet anticorps Lapin Polyclonal détecte spécifiquement TUB dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Cheval, Chien, Lapin et Cobaye.

Aperçu rapide pour TUB anticorps (N-Term) (ABIN2777955)

Antigène: TUB (Tubby Homolog (TUB))

Reactivité: Humain, Souris, Rat, Cheval, Chien, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TUB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-TUB anticorps

Épitope: N-Term

Fonction: TUB Antibody - N-terminal region

Séquence: DSLASVQLGA TRPTAPASAK RTKAAATAGG QGGAARKEKK GKHKGTSGPA

Homologie: Dog: 92%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against TUB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TUB

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33467-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur TUB

Antigène: TUB (Tubby Homolog (TUB))

Autre désignation: TUB

Sujet:

Background Information: TUB functions in signal transduction from heterotrimeric G protein-coupled receptors. It could be involved in the hypothalamic regulation of body weight. This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene Name: Tubby homolog (mouse)

Alternative Symbols: rd5, RDOB

Protein Name: Tubby protein homolog

Poids moléculaire: 62kDa

ID gène: 7275

NCBI Accession: NP_003311

UniProt: P50607

Pathways: Signalisation RTK, Sensory Perception of Sound