Claudin 11 anticorps (C-Term)

N° du produit ABIN2778048

Détail du produit anti-Claudin 11 anticorps

Antigène: Claudin 11 (CLDN11)

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 11 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: VSFGYSLYAG WIGAVLCLVG GCVILCCAGD AQAFGENRFY YTAGSSSPTH

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against CLDN11. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CLDN11

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 207 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Claudin 11

Antigène: Claudin 11 (CLDN11)

Autre désignation: CLDN11 (CLDN11 Produits)

Synonymes: anticorps cldn11, anticorps fb97c11, anticorps wu:fb97c11, anticorps claudin-11, anticorps CLDN11, anticorps Claudin-11, anticorps DKFZp459H2322, anticorps OSP, anticorps OTM, anticorps Claudin11, anticorps Osp, anticorps Otm, anticorps claudin 11b, anticorps claudin 11, anticorps cldn11b, anticorps CLDN11, anticorps Cldn11

Sujet: CLDN11 belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.The protein encoded by this gene belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.
Alias Symbols: OSP, OTM
Protein Interaction Partner: UBC, TSPAN3, TSPAN4,
Protein Size: 207

Poids moléculaire: 22 kDa

ID gène: 5010

NCBI Accession: NM_005602, NP_005593

UniProt: O75508

Pathways: Hepatitis C