BMI1 anticorps (Middle Region)
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- Antigène Voir toutes BMI1 Anticorps
- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache), Cheval, Cobaye, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BMI1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- MDIPNTFQID VMYEEEPLKD YYTLMDIAYI YTWRRNGPLP LKYRVRPTCK
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 77%
- Attributs du produit
- This is a rabbit polyclonal antibody against Bmi1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product BMI1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 324 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
- Autre désignation
- Bmi1 (BMI1 Produits)
- Synonymes
- anticorps FLVI2/BMI1, anticorps PCGF4, anticorps RNF51, anticorps AW546694, anticorps Bmi-1, anticorps Pcgf4, anticorps bmi1, anticorps pcgf4, anticorps psc1, anticorps wu:fb17g03, anticorps wu:fd18f06, anticorps BMI-1, anticorps pcgf4b, anticorps bmi-1, anticorps bmi1-a, anticorps bmi1-b, anticorps bmi1b, anticorps rnf51, anticorps xbmi-1, anticorps BMI1 proto-oncogene, polycomb ring finger, anticorps BMI1 polycomb ring finger oncogene, anticorps Bmi1 polycomb ring finger oncogene, anticorps bmi1 polycomb ring finger oncogene 1a, anticorps bmi1 polycomb ring finger oncogene 1b, anticorps BMI1 proto-oncogene, polycomb ring finger L homeolog, anticorps BMI1, anticorps LOC100230513, anticorps Bmi1, anticorps bmi1a, anticorps bmi1b, anticorps bmi1.L
- Sujet
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Bmi1 is a component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Alias Symbols: AW546694, Bmi-1, Pcgf4
Protein Interaction Partner: Rnf2, Eed, Aurkb, Phc2, RING1, Gata6, Mph1, Cbfb, Runx1, Cdkn2a, HIST2H2AC, Slc11a1, Dnmt3b, Kdm2b, Phc1, Cbx2, Phc3, Dmap1, CBX8, SCMH1, CBX4, SMARCA5, HSPA4,
Protein Size: 324 - Poids moléculaire
- 37 kDa
- ID gène
- 12151
- NCBI Accession
- NM_007552, NP_031578
- UniProt
- P25916
- Pathways
- Cycle Cellulaire, Autophagy
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