BMI1 anticorps (Middle Region)

N° du produit ABIN2778059

Cet anticorps Lapin Polyclonal détecte spécifiquement BMI1 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache), Cheval, Cobaye et Poisson zèbre (Danio rerio).

Aperçu rapide pour BMI1 anticorps (Middle Region) (ABIN2778059)

Antigène: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Reactivité: Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache), Cheval, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMI1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BMI1 anticorps

Épitope: Middle Region

Fonction: Bmi1 Antibody - middle region

Séquence: MDIPNTFQID VMYEEEPLKD YYTLMDIAYI YTWRRNGPLP LKYRVRPTCK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 77%

Attributs du produit: This is a rabbit polyclonal antibody against Bmi1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33655-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur BMI1

Antigène: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Autre désignation: Bmi1

Sujet:

Background Information: Bmi1 is a component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

Gene Name: Bmi1 polycomb ring finger oncogene

Alternative Symbols: Bmi, Bmi-, Pcgf, Bmi-1, Pcgf4, AW546694

Protein Name: Polycomb complex protein BMI-1

Poids moléculaire: 37kDa

ID gène: 12151

NCBI Accession: NP_031578

UniProt: P25916

Pathways: Cycle Cellulaire, Autophagy