Membralin anticorps (Middle Region)
Aperçu rapide pour Membralin anticorps (Middle Region) (ABIN2778282)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- YDDILMSSVK GLAENEENKG FLRNVVSGEH YRFVSMWMAR TSYLAAFAIM
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against C19ORF6. It was validated on Western Blot and immunohistochemistry.
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Purification
- Protein A purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human C19ORF6
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 408 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Membralin (TMEM259) (Transmembrane Protein 259 (TMEM259))
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Autre désignation
- C19ORF6
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Sujet
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Human membralin is unique and does not share significant sequence homology with other human genes, only membralins of other species. The membralin gene contains 11 exons which encode at least two spliced variants in human cancer. The long form of membralin (membralin-1) comprises all 11 exons, encoding a protein of 620-amino acids long and the short form of membralin (membralin-3) contains all exons except for exon 10, encoding a protein of 408 amino acids. Expression of different membralin isoforms depends on tissue type. The long form, membralin-1, is expressed in ovarian and colorectal carcinomas but not in breast or pancreatic carcinomas, which express only the short splice form, membralin-3. Recent studies suggest that membralin is a novel tumor-associated marker in ovarian serous carcinomas
Alias Symbols: MBRL, ASBABP1, R32184_3, MEMBRALIN, C19ORF6
Protein Interaction Partner: ADRB2, UBC, TMEM173, ARSE,
Protein Size: 408 -
Poids moléculaire
- 46 kDa
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ID gène
- 91304
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NCBI Accession
- NM_033420, NP_219488
Antigène
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