MED17 anticorps (N-Term)

N° du produit ABIN2778320

Cet anticorps Lapin Polyclonal détecte spécifiquement MED17 dans WB, IHC et ChIP. Il présente une réactivité envers Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval et Lapin.

Aperçu rapide pour MED17 anticorps (N-Term) (ABIN2778320)

Antigène: MED17 (Mediator Complex Subunit 17 (MED17))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED17 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)

Détail du produit anti-MED17 anticorps

Épitope: N-Term

Séquence: AAQILLKGAE RLTKSVTENQ ENKLQRDFNS ELLRLRQHWK LRKVGDKILG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CRSP6. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CRSP6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 651 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MED17

Antigène: MED17 (Mediator Complex Subunit 17 (MED17))

Autre désignation: CRSP6

Sujet: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by CRSP6 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
Alias Symbols: CRSP6, CRSP77, DRIP80, TRAP80
Protein Interaction Partner: UBC, BRCA1, CDK19, CDK8, MED26, POLR2C, ESR2, MED19, FBXW7, EPAS1, TFIP11, MED24, MED21, MED14, MED11, MED28, WDR33, CPSF2, UBD, BCL6, SMARCA4, SUZ12, MED10, CTDP1, SREBF1, MED25, MED15, TRA, MED1, OBFC1, MED18, ZC3H13, MED12, QKI, TRIP4, TADA2A, SUPT7L,
Protein Size: 651

Poids moléculaire: 73 kDa

ID gène: 9440

NCBI Accession: NM_004268, NP_004259

UniProt: Q9NVC6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha