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HDAC4 anticorps (N-Term)

HDAC4 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Poisson zèbre (Danio rerio), Cobaye, Cheval WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2778341
  • Antigène Voir toutes HDAC4 Anticorps
    HDAC4 (Histone Deacetylase 4 (HDAC4))
    Épitope
    • 15
    • 14
    • 11
    • 9
    • 8
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 115
    • 51
    • 34
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Boeuf (Vache), Poisson zèbre (Danio rerio), Cobaye, Cheval
    Hôte
    • 103
    • 13
    • 1
    Lapin
    Clonalité
    • 103
    • 14
    Polyclonal
    Conjugué
    • 73
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HDAC4 est non-conjugé
    Application
    • 89
    • 51
    • 29
    • 16
    • 14
    • 13
    • 13
    • 10
    • 9
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    EKQHREQKLQ QLKNKEKGKE SAVASTEVKM KLQEFVLNKK KALAHRNLNH
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 85%
    Attributs du produit
    This is a rabbit polyclonal antibody against HDAC4. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human HDAC4
    Top Product
    Discover our top product HDAC4 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 1084 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    HDAC4 (Histone Deacetylase 4 (HDAC4))
    Autre désignation
    HDAC4 (HDAC4 Produits)
    Synonymes
    anticorps CG1770, anticorps DHDAC4, anticorps Dmel\\CG1770, anticorps GC1770, anticorps HDAC, anticorps HDAC4a, anticorps dHDAC4, anticorps dmHDA405, anticorps hdac4, anticorps dana_GLEANR_19966, anticorps DanaGF18710, anticorps GF18710, anticorps HDAC4, anticorps AHO3, anticorps BDMR, anticorps HA6116, anticorps HD4, anticorps HDAC-4, anticorps HDAC-A, anticorps HDACA, anticorps 4932408F19Rik, anticorps AI047285, anticorps wu:fa96d08, anticorps wu:fc56f08, anticorps zgc:152701, anticorps histone deacetylase 4, anticorps hypothetical protein, anticorps Histone deacetylase 4, anticorps GF18710 gene product from transcript GF18710-RC, anticorps PTRG_03699, anticorps PGTG_15512, anticorps HDAC4, anticorps Dana\GF18710, anticorps Hdac4, anticorps hdac4
    Sujet
    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC4 belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: HA6116, HD4, HDAC-A, HDACA, KIAA0288, AHO3, BDMR, HDAC-4
    Protein Interaction Partner: UBC, TP53BP1, KRT31, MTUS2, KDM5B, HDAC5, NCOR2, PNMA1, KRT38, YWHAG, KRT40, CCDC136, RINT1, ANKRA2, EFEMP2, LDOC1, GSK3B, GOLGA2, CDR2, BCL6, YWHAQ, YWHAB, YWHAE, SIRT1, UBE2I, TBL1XR1, HDAC4, NCOR1, YWHAZ, YWHAH, SFN, MIF4GD, ZBTB7B, APP, ATF3, JDP2, Bt
    Protein Size: 1084
    Poids moléculaire
    119 kDa
    ID gène
    9759
    NCBI Accession
    NM_006037, NP_006028
    UniProt
    P56524
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
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