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RNF8 anticorps (C-Term)

L’anticorps Lapin Polyclonal anti-RNF8 a été validé pour WB et IHC. Il convient pour détecter RNF8 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cheval, Porc, Chien et Lapin.
N° du produit ABIN2778597

Aperçu rapide pour RNF8 anticorps (C-Term) (ABIN2778597)

Antigène

Voir toutes RNF8 Anticorps
RNF8 (Ring Finger Protein 8 (RNF8))

Reactivité

  • 55
  • 29
  • 21
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat, Boeuf (Vache), Cheval, Porc, Chien, Lapin

Hôte

  • 50
  • 4
  • 1
  • 1
Lapin

Clonalité

  • 54
  • 2
Polyclonal

Conjugué

  • 26
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp RNF8 est non-conjugé

Application

  • 50
  • 19
  • 13
  • 11
  • 5
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Épitope

    • 8
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Séquence

    MEELNRSKKD FEAIIQAKNK ELEQTKEEKE KMQAQKEEVL SHMNDVLENE

    Homologie

    Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%

    Attributs du produit

    This is a rabbit polyclonal antibody against RNF8. It was validated on Western Blot and immunohistochemistry.

    Purification

    Protein A purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the C terminal region of human RNF8
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 485 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    RNF8 (Ring Finger Protein 8 (RNF8))

    Autre désignation

    RNF8

    Sujet

    RNF8 contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins.The protein encoded by this gene contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
    Alias Symbols: FLJ12013, KIAA0646
    Protein Interaction Partner: TMEM79, HOMEZ, SEPT3, RBFOX2, PNMA2, USP16, WASL, HERC2, MAD1L1, VCP, TNFRSF1A, TNF, BCL10, UBE2N, UBC, NEDD8, JMJD1C, MDC1, EXOSC2, MDM2, BLM, SEPT8, SEPT7, RPSA, H2AFX, RL2, HIST2H2BE, HIST2H2AC, PCNA, RAD50, NBN, MRE11A, UBE2E3, UBE2V1, UBE2E2, UBE2E1,
    Protein Size: 485

    Poids moléculaire

    55 kDa

    ID gène

    9025

    NCBI Accession

    NM_003958, NP_003949

    UniProt

    O76064

    Pathways

    Production of Molecular Mediator of Immune Response
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