RNF8 anticorps (C-Term)

N° du produit ABIN2778597

L’anticorps anti-RNF8 Polyclonal Lapin est utilisé pour la détection de RNF8 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cheval, Porc, Chien et Lapin. Il a été validé pour WB et IHC.

Aperçu rapide pour RNF8 anticorps (C-Term) (ABIN2778597)

Antigène: RNF8 (Ring Finger Protein 8 (RNF8))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Porc, Chien, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-RNF8 anticorps

Épitope: C-Term

Fonction: RNF8 Antibody - C-terminal region

Séquence: MEELNRSKKD FEAIIQAKNK ELEQTKEEKE KMQAQKEEVL SHMNDVLENE

Homologie: Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RNF8. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human RNF8

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8110891

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur RNF8

Antigène: RNF8 (Ring Finger Protein 8 (RNF8))

Autre désignation: RNF8

Sujet:

Background Information: RNF8 contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins.The protein encoded by this gene contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Gene Name: Ring finger protein 8, E3 ubiquitin protein ligase

Alternative Symbols: hRNF8

Protein Name: E3 ubiquitin-protein ligase RNF8

Poids moléculaire: 55kDa

ID gène: 9025

NCBI Accession: NP_003949

UniProt: O76064

Pathways: Production of Molecular Mediator of Immune Response