SIRT5 anticorps (Middle Region)

N° du produit ABIN2778620

Détail du produit anti-SIRT5 anticorps

Antigène: SIRT5 (Sirtuin 5 (SIRT5))

Épitope: Middle Region

Reactivité: Humain, Souris, Boeuf (Vache), Chévre, Lapin, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIRT5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: PICPALSGKG APEPGTQDAS IPVEKLPRCE EAGCGGLLRP HVVWFGENLD

Homologie: Cow: 79%, Goat: 79%, Human: 100%, Mouse: 79%, Pig: 86%, Rabbit: 86%

Attributs du produit: This is a rabbit polyclonal antibody against SIRT5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SIRT5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 310 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SIRT5

Antigène: SIRT5 (Sirtuin 5 (SIRT5))

Autre désignation: SIRT5 (SIRT5 Produits)

Synonymes: anticorps SIR2L5, anticorps 0610012J09Rik, anticorps 1500032M05Rik, anticorps AV001953, anticorps zgc:92288, anticorps sirt5-a, anticorps SIRT5, anticorps sir2l5, anticorps sirtuin 5, anticorps sirtuin 5 L homeolog, anticorps SIRT5, anticorps Sirt5, anticorps sirt5, anticorps sirt5.L, anticorps CC1G_00083

Sujet: SIRT5 is included in class III of the sirtuin family which ischaracterized by a sirtuin core domain. Human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in two transcript variants.
Alias Symbols: SIR2L5
Protein Interaction Partner: SIRT3, UBC, HECW2, APP, RELA,
Protein Size: 310

Poids moléculaire: 34 kDa

ID gène: 23408

NCBI Accession: NM_012241, NP_036373

UniProt: Q9NXA8

Pathways: SARS-CoV-2 Protein Interactome