Cytokeratin 18 anticorps (N-Term)

N° du produit ABIN2778669

L’anticorps Lapin Polyclonal anti-Cytokeratin 18 a été validé pour WB et IHC. Il convient pour détecter Cytokeratin 18 dans des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin et Cobaye.

Aperçu rapide pour Cytokeratin 18 anticorps (N-Term) (ABIN2778669)

Antigène: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cytokeratin 18 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Cytokeratin 18 anticorps

Épitope: N-Term

Séquence: TRSTFSTNYR SLGSVQAPSY GARPVSSAAS VYAGAGGSGS RISVSRSTSF

Homologie: Cow: 86%, Dog: 92%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against KRT18. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human KRT18

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 430 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Cytokeratin 18

Antigène: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Autre désignation: KRT18

Sujet: KRT18 (Keratin 18) is type I intermediate filament chain. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis.KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: K18, CYK18
Protein Interaction Partner: KRT18, GOLGA2, UBC, HAUS1, CCDC146, MDM2, EED, HNRNPU, FLII, FKBP3, DDX1, C14orf166, RTCB, CNOT1, SEC16A, RPL14, RFC2, UPF2, BBS7, PAN2, BBS4, BBS2, BBS1, SMARCD1, ORC5, NOS2, KRT8, KPNA2, ITGA4, HRAS, GRN, FN1, EP300, ATF2, CDH1, CDC5L, YTHDC1, PIAS4, TX
Protein Size: 430

Poids moléculaire: 47 kDa

ID gène: 3875

NCBI Accession: NM_000224, NP_000215

UniProt: P05783

Pathways: Apoptose, Caspase Cascade in Apoptosis