SNRNP70 anticorps (N-Term)

N° du produit ABIN2778715

Cet anticorps Lapin Polyclonal détecte spécifiquement SNRNP70 dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye, Lapin et Cheval et a été mentionné dans 2+ publications.

Aperçu rapide pour SNRNP70 anticorps (N-Term) (ABIN2778715)

Antigène: SNRNP70 (Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70))

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye, Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNRNP70 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SNRNP70 anticorps

Épitope: N-Term

Séquence: PHNDPNAQGD AFKTLFVARV NYDTTESKLR REFEVYGPIK RIHMVYSKRS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SNRP70. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SNRP70

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 437 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SNRNP70 (ABIN2778715)

Wang, Mueller, Hertel, Cambi: "G Run-mediated recognition of proteolipid protein and DM20 5' splice sites by U1 small nuclear RNA is regulated by context and proximity to the splice site." dans: The Journal of biological chemistry, Vol. 286, Issue 6, pp. 4059-71, (2011) (PubMed).

Wang, Cambi: "Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs." dans: The Journal of biological chemistry, Vol. 284, Issue 17, pp. 11194-204, (2009) (PubMed).

Détails sur SNRNP70

Antigène: SNRNP70 (Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70))

Autre désignation: SNRP70

Sujet: SNRP70 contains 1 RRM (RNA recognition motif) domain and mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
Alias Symbols: RPU1, Snp1, U1AP, U170K, U1RNP, RNPU1Z, SNRP70, U1-70K
Protein Interaction Partner: IL32, UBC, NEDD8, LIN28A, EZH2, SUZ12, EED, RNF2, rev, WBP4, SRPK2, SRPK1, MYC, SRPK3, HDAC2, PAN2, SMURF2, PRPF40A, CDKL3, RNF11, PRKD2, SKIL, RELA, RASGRF1, SMAD9, SMAD5, SMAD4, SMAD3, SMAD2, CHERP, PRMT5, UBL4A, VCAM1, SMAD1, ITGA4, IL7R, IFIT3, IFIT1,
Protein Size: 437

Poids moléculaire: 52 kDa

ID gène: 6625

NCBI Accession: NM_003089, NP_003080

UniProt: P08621