Splicing factor U2AF 26 kDa subunit (U2AF1L4) (N-Term) anticorps

N° du produit ABIN2778747

L’anticorps anti-Splicing factor U2AF 26 kDa subunit Polyclonal Lapin est utilisé pour la détection de Splicing factor U2AF 26 kDa subunit dans des échantillons de Humain, Chien, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio) et Chévre. Il a été validé pour WB.

Aperçu rapide pour Splicing factor U2AF 26 kDa subunit (U2AF1L4) (N-Term) anticorps (ABIN2778747)

Antigène: Splicing factor U2AF 26 kDa subunit (U2AF1L4)

Reactivité: Humain, Chien, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB)

Détail du produit

Épitope: N-Term

Séquence: KIGVCRHGDR CSRLHNKPTF SQTIVLLNLY RNPQNTAQTA DGSHCHVSDV

Homologie: Cow: 100%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against U2AF1L4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human U2AF1L4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détail du antigène

Antigène: Splicing factor U2AF 26 kDa subunit (U2AF1L4)

Autre désignation: U2AF1L4

Sujet: U2AF1L4 is a RNA-binding protein that function as a pre-mRNA splicing factor. It plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. It acts by enhancing the binding of U2AF2 to weak pyrimidine tracts and also participates in the regulation of alternative pre-mRNA splicing. It activates exon 5 skipping of PTPRC during T-cell activation, an event reversed by GFI1. U2AF1L4 binds to RNA at the AG dinucleotide at the 3'-splice site.
Protein Interaction Partner: MDM2, SUZ12, UBC, ELAVL1, GIGYF2,
Protein Size: 220

Poids moléculaire: 24 kDa

ID gène: 199746

UniProt: Q8WU68