SNRNP70 anticorps (C-Term)

N° du produit ABIN2778829

Cet anticorps Lapin Polyclonal détecte spécifiquement SNRNP70 dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye et Lapin et a été mentionné dans 3+ publications.

Aperçu rapide pour SNRNP70 anticorps (C-Term) (ABIN2778829)

Antigène: SNRNP70 (Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNRNP70 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SNRNP70 anticorps

Épitope: C-Term

Séquence: RERERKEELR GGGGDMAEPS EAGDAPPDDG PPGELGPDGP DGPEEKGRDR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SNRP70. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human SNRP70

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 437 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SNRNP70 (ABIN2778829)

Franklin, Chen, Mitchell-Jordan, Ren, Wang, Vondriska: "Quantitative analysis of the chromatin proteome in disease reveals remodeling principles and identifies high mobility group protein B2 as a regulator of hypertrophic growth." dans: Molecular & cellular proteomics : MCP, Vol. 11, Issue 6, pp. M111.014258, (2012) (PubMed).

Serini, Fasano, Piccioni, Monego, Cittadini, Celleno, Ranelletti, Calviello: "DHA induces apoptosis and differentiation in human melanoma cells in vitro: involvement of HuR-mediated COX-2 mRNA stabilization and ?-catenin nuclear translocation." dans: Carcinogenesis, Vol. 33, Issue 1, pp. 164-73, (2011) (PubMed).

Franklin, Zhang, Chen, Paulsson, Mitchell-Jordan, Li, Ping, Vondriska: "Specialized compartments of cardiac nuclei exhibit distinct proteomic anatomy." dans: Molecular & cellular proteomics : MCP, Vol. 10, Issue 1, pp. M110.000703, (2011) (PubMed).

Détails sur SNRNP70

Antigène: SNRNP70 (Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70))

Autre désignation: SNRP70

Sujet: SNRP70 contains 1 RRM (RNA recognition motif) domain and mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
Alias Symbols: RNPU1Z, RPU1, U170K, U1AP, U1RNP, Snp1, SNRP70, U1-70K
Protein Interaction Partner: IL32, UBC, NEDD8, LIN28A, EZH2, SUZ12, EED, RNF2, rev, WBP4, SRPK2, SRPK1, MYC, SRPK3, HDAC2, PAN2, SMURF2, PRPF40A, CDKL3, RNF11, PRKD2, SKIL, RELA, RASGRF1, SMAD9, SMAD5, SMAD4, SMAD3, SMAD2, CHERP, PRMT5, UBL4A, VCAM1, SMAD1, ITGA4, IL7R, IFIT3, IFIT1,
Protein Size: 437

Poids moléculaire: 51 kDa

ID gène: 6625

NCBI Accession: NM_003089, NP_003080

UniProt: P08621