EIF2S1 anticorps (C-Term)

N° du produit ABIN2778883

L’anticorps Lapin Polyclonal anti-EIF2S1 a été validé pour WB et IHC. Il convient pour détecter EIF2S1 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Lapin, Cobaye, Cheval, Chévre et Saccharomyces cerevisiae.

Aperçu rapide pour EIF2S1 anticorps (C-Term) (ABIN2778883)

Antigène: EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Lapin, Cobaye, Cheval, Chévre, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF2S1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-EIF2S1 anticorps

Épitope: C-Term

Séquence: RGVFNVQMEP KVVTDTDETE LARQMERLER ENAEVDGDDD AEEMEAKAED

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against EIF2S1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human EIF2S1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 315 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur EIF2S1

Antigène: EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))

Autre désignation: EIF2S1

Sujet: The translation initiation factor eIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is composed of 3 nonidentical subunits, alpha (36 kD), beta (38 kD), and gamma (52 kD). The rate of formation of the ternary complex is modulated by the phosphorylation state of eIF2-alpha.The translation initiation factor eIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is composed of 3 nonidentical subunits, alpha (36 kD), beta (38 kD, MIM 603908), and gamma (52 kD, MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of eIF2-alpha (Ernst et al., 1987).[supplied by OMIM].
Alias Symbols: EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A
Protein Interaction Partner: HUWE1, UBC, SUMO2, SUMO3, RPA3, RPA2, RPA1, RNF2, EIF2S3, DARS, RPS27L, EEF1E1, AIMP1, EIF2S2, RPLP0, RPL27A, RPL15, RPL13, RPL7A, QARS, MARS, MAP4, TERT, NPM1, MMS19, Dlg4, VCAM1, UPF1, ITGA4, FN1, CSNK2A1, EIF2AK2, NCOA5, POP1, STRN, YBX1, DDX1, TMED9,
Protein Size: 315

Poids moléculaire: 35 kDa

ID gène: 1965

NCBI Accession: NM_004094, NP_004085

UniProt: P05198

Pathways: Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C