STAU1/Staufen anticorps (N-Term)

N° du produit ABIN2778907

L’anticorps Lapin Polyclonal anti-STAU1/Staufen a été validé pour WB et IHC. Il convient pour détecter STAU1/Staufen dans des échantillons de Humain, Rat, Souris, Cheval, Boeuf (Vache), Cobaye, Chien, Lapin et Porc.

Aperçu rapide pour STAU1/Staufen anticorps (N-Term) (ABIN2778907)

Antigène: STAU1/Staufen (STAU1) (Staufen Double-Stranded RNA Binding Protein 1 (STAU1))

Reactivité: Humain, Rat, Souris, Cheval, Boeuf (Vache), Cobaye, Chien, Lapin, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STAU1/Staufen est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-STAU1/Staufen anticorps

Épitope: N-Term

Séquence: LSVGGQQFNG KGKTRQAAKH DAAAKALRIL QNEPLPERLE VNGRESEEEN

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against STAU1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human STAU1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 577 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur STAU1/Staufen

Antigène: STAU1/Staufen (STAU1) (Staufen Double-Stranded RNA Binding Protein 1 (STAU1))

Autre désignation: STAU1

Sujet: STAU1(Staufen) is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR.
Alias Symbols: STAU
Protein Interaction Partner: LONRF1, GLRX3, ZMAT3, NXT1, SPRTN, MATR3, EIF4A3, NUP155, PRDX6, NPEPPS, DDX23, DDX21, AIFM1, INA, ATP6V0D1, SART1, RPL14, AP3D1, CPNE3, IQGAP1, PABPC4, EIF3D, EIF3B, EIF3A, PRKRA, KHSRP, IRS4, SLC25A11, SMC1A, PABPN1, DDX39B, TUBA1A, MOGS, YWHAZ, XPO1, V
Protein Size: 577

Poids moléculaire: 63 kDa

ID gène: 6780

NCBI Accession: NM_017453, NP_059347

UniProt: O95793

Pathways: Asymmetric Protein Localization