EIF4E2 anticorps (N-Term)
Aperçu rapide pour EIF4E2 anticorps (N-Term) (ABIN2778915)
Antigène
Voir toutes EIF4E2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- KDDDSGDHDQ NEENSTQKDG EKEKTERDKN QSSSKRKAVV PGPAEHPLQY
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Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against EIF4E2. It was validated on Western Blot and immunohistochemistry.
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Purification
- Protein A purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human EIF4E2
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 245 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Characterizing the interaction of the mammalian eIF4E-related protein 4EHP with 4E-BP1." dans: FEBS letters, Vol. 564, Issue 1-2, pp. 58-62, (2004) (PubMed).
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: "Characterizing the interaction of the mammalian eIF4E-related protein 4EHP with 4E-BP1." dans: FEBS letters, Vol. 564, Issue 1-2, pp. 58-62, (2004) (PubMed).
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- EIF4E2 (Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2))
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Autre désignation
- EIF4E2
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Sujet
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EIF4E2 belongs to the eukaryotic initiation factor 4E family. It recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
Alias Symbols: 4EHP, IF4e, 4E-LP, EIF4EL3
Protein Interaction Partner: USHBP1, CARD9, PRDM14, HOMEZ, TRIM54, NECAB2, ADAMTSL4, AMOTL2, SPAG5, SPRY2, HUWE1, TMCC2, MAGED1, TCF4, TADA2A, TRIM27, REL, MYOG, KRT31, KRT19, KRT13, CDR2, AES, MAPRE3, NOTCH2NL, KRTAP10-8, KRTAP10-5, KRTAP10-9, ZBTB9, SPERT, USP54, MIPOL1, KRT40, UBX
Protein Size: 245 -
Poids moléculaire
- 27 kDa
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ID gène
- 9470
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NCBI Accession
- NM_004846, NP_004837
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UniProt
- O60573
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Pathways
- SARS-CoV-2 Protein Interactome
Antigène
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