HNRNPF anticorps (C-Term)

N° du produit ABIN2778920

Cet anticorps Lapin Polyclonal détecte spécifiquement HNRNPF dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Cobaye, Lapin, Chien et Cheval et a été mentionné dans 1 publication.

Aperçu rapide pour HNRNPF anticorps (C-Term) (ABIN2778920)

Antigène: HNRNPF (Heterogeneous Nuclear Ribonucleoprotein F (HNRNPF))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Lapin, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HNRNPF est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-HNRNPF anticorps

Épitope: C-Term

Séquence: LNSTTGASNG AYSSQVMQGM GVSAAQATYS GLESQSVSGC YGAGYSGQNS

Homologie: Cow: 91%, Dog: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against HNRPF. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human HNRPF

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 415 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-HNRNPF (ABIN2778920)

White, Gonsior, Bauer, Krämer-Albers, Luhmann, Trotter: "Heterogeneous nuclear ribonucleoprotein (hnRNP) F is a novel component of oligodendroglial RNA transport granules contributing to regulation of myelin basic protein (MBP) synthesis." dans: The Journal of biological chemistry, Vol. 287, Issue 3, pp. 1742-54, (2012) (PubMed).

Détails sur HNRNPF

Antigène: HNRNPF (Heterogeneous Nuclear Ribonucleoprotein F (HNRNPF))

Autre désignation: HNRPF

Sujet: HNRPF belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH.
Alias Symbols: HNRPF, mcs94-1, OK/SW-cl.23
Protein Interaction Partner: HSFY1, C1orf94, CCDC33, EIF4ENIF1, RBFOX2, IKZF3, HNRNPUL1, HNRNPM, FUS, TFG, DZIP3, UBC, AES, NEDD1, CEP250, SUMO2, SUMO3, TP53, CDC20, STAU1, IVNS1ABP, SUMO1, NEDD8, MDM2, WWOX, RPA3, RPA2, RPA1, ERG, EED, rev, PRPF40A, OSGEP, ABCF3, DNAAF5, PPME1, PPP1
Protein Size: 415

Poids moléculaire: 46 kDa

ID gène: 3185

NCBI Accession: NM_004966, NP_004957

UniProt: P52597