RBM14 anticorps (N-Term)
Aperçu rapide pour RBM14 anticorps (N-Term) (ABIN2778973)
Antigène
Voir toutes RBM14 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- YAFVHMEKEA DAKAAIAQLN GKEVKGKRIN VELSTKGQKK GPGLAVQSGD
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against RBM14. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human RBM14
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 669 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Gene amplification and associated loss of 5' regulatory sequences of CoAA in human cancers." dans: Oncogene, Vol. 26, Issue 6, pp. 822-35, (2007) (PubMed).
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: "Gene amplification and associated loss of 5' regulatory sequences of CoAA in human cancers." dans: Oncogene, Vol. 26, Issue 6, pp. 822-35, (2007) (PubMed).
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- RBM14 (RNA Binding Motif Protein 14 (RBM14))
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Autre désignation
- RBM14
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Sujet
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RBM14 contains 2 RRM (RNA recognition motif) domains. Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1.
Alias Symbols: COAA, DKFZp779J0927, SIP, SYTIP1, PSP2, TMEM137
Protein Interaction Partner: UBC, SUMO2, SUMO3, CEP250, DROSHA, MDM2, SMURF2, RPA3, RPA2, RPA1, EZH2, BMI1, RNF2, SUZ12, EED, MAPK15, CDK15, CDK14, HDAC9, HDAC11, WHSC1, VCAM1, TRAF3, ITGA4, FN1, ESR1, ZC3H18, FTSJ3, RBM25, TRMT112, HP1BP3, PRPF19, RBMX, RSL1D1, PRPF6, HNRNPH1, RCC1,
Protein Size: 669 -
Poids moléculaire
- 69 kDa
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ID gène
- 10432
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NCBI Accession
- NM_006328, NP_006319
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UniProt
- Q96PK6
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
Antigène
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