IRAK3 anticorps (C-Term)

N° du produit ABIN2779025

Détail du produit anti-IRAK3 anticorps

Antigène: IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRAK3 est non-conjugé

Application: Western Blotting (WB)

Séquence: NTLESTQASL YFAEDPPTSL KSFRCPSPLF LENVPSIPVE DDESQNNNLL

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against IRAK3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human IRAK3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 596 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur IRAK3

Antigène: IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

Autre désignation: IRAK3 (IRAK3 Produits)

Synonymes: anticorps IRAK3, anticorps si:dkey-150i15.2, anticorps ASRT5, anticorps IRAKM, anticorps IrakM, anticorps 4833428C18Rik, anticorps AI563835, anticorps IRAK-M, anticorps interleukin 1 receptor associated kinase 3, anticorps interleukin-1 receptor-associated kinase 3, anticorps IRAK3, anticorps irak3, anticorps Irak3

Sujet: IRAK3 contains 1 protein kinase domain and 1 death domain and belongs to the Ser/Thr protein kinase family, Pelle subfamily. It inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.
Alias Symbols: ASRT5, IRAKM
Protein Interaction Partner: CDCA5, NSA2, LDB1, NTRK3, NONO, HSP90AA1, HOXB7, FOLR1, ECM1, COPB1, CD14, ATP6V0B, ADH1B, IRAK1, UBC, IRAK4, IRAK2, TICAM2, IRAK3, TRAF6, MYD88,
Protein Size: 596

Poids moléculaire: 66 kDa

ID gène: 11213

NCBI Accession: NM_007199, NP_009130

UniProt: Q9Y616

Pathways: Signalisation TLR, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades