CDKN2AIP anticorps (C-Term)
Aperçu rapide pour CDKN2AIP anticorps (C-Term) (ABIN2779115)
Antigène
Voir toutes CDKN2AIP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- AIEALKATLD VFFVPLKELA DLPQNKSSQE SIVCELRCKS VYLGTGCGKS
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against CARF. It was validated on Western Blot and immunohistochemistry.
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Purification
- Protein A purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human CARF
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 580 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CDKN2AIP (CDKN2A Interacting Protein (CDKN2AIP))
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Autre désignation
- CARF
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Sujet
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CARF was first cloned as a novel binding partner of ARF from a yeast-interactive screen. CARF and ARF colocalize in the perinucleolar region and have a collaborative function. In the nucleoplasm, CARF interacts with p53 and enhances its function. The p53 downregulates CARF in a negative feedback regulatory loop and may also involve p53 antagonist HDM2.
Alias Symbols: CARF
Protein Interaction Partner: UBC, XRN2, RPA3, RPA2, RPA1, WHSC1, VCP, Cdkn2a, MDC1, BRCA1, BARD1, GGH, EPHX1, MDM2, CUL3, SUMO2, RAD21, DHX58, Clp1,
Protein Size: 580 -
Poids moléculaire
- 64 kDa
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ID gène
- 55602
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NCBI Accession
- NM_017632, NP_060102
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UniProt
- Q9NXV6
Antigène
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