RGS4 anticorps (C-Term)

N° du produit ABIN2779301

Cet anticorps Lapin Polyclonal détecte spécifiquement RGS4 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Lapin, Mouton, Cobaye, Chien et Cheval.

Aperçu rapide pour RGS4 anticorps (C-Term) (ABIN2779301)

Antigène: RGS4 (Regulator of G-Protein Signaling 4 (RGS4))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Mouton, Cobaye, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RGS4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RGS4 anticorps

Épitope: C-Term

Séquence: EAQKKIFNLM EKDSYRRFLK SRFYLDLVNP SSCGAEKQKG AKSSADCASL

Homologie: Cow: 86%, Dog: 92%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 86%

Attributs du produit: This is a rabbit polyclonal antibody against RGS4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human RGS4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 205 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RGS4

Antigène: RGS4 (Regulator of G-Protein Signaling 4 (RGS4))

Autre désignation: RGS4

Sujet: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein negatively regulates signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37 % identical to RGS1 and 97 % identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.
Alias Symbols: MGC2124, MGC60244, RGP4, SCZD9
Protein Interaction Partner: GABBR1, KRIT1, PLCB1, COPB2, GNAQ, COPB1, ERBB3, PTAFR, GNAI2, GNAO1, GNAI1, CALM1, GNAI3, GNAT1,
Protein Size: 205

Poids moléculaire: 23 kDa

ID gène: 5999

NCBI Accession: NM_005613, NP_005604

UniProt: P49798

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling