RGS4 anticorps (C-Term)

N° du produit ABIN2779301

Détail du produit anti-RGS4 anticorps

Antigène: RGS4 (Regulator of G-Protein Signaling 4 (RGS4))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Mouton, Cobaye, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RGS4 est non-conjugé

Application: Western Blotting (WB)

Séquence: EAQKKIFNLM EKDSYRRFLK SRFYLDLVNP SSCGAEKQKG AKSSADCASL

Homologie: Cow: 86%, Dog: 92%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 86%

Attributs du produit: This is a rabbit polyclonal antibody against RGS4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human RGS4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 205 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RGS4

Antigène: RGS4 (Regulator of G-Protein Signaling 4 (RGS4))

Autre désignation: RGS4 (RGS4 Produits)

Synonymes: anticorps RGP4, anticorps SCZD9, anticorps AA004315, anticorps AA597169, anticorps ESTM48, anticorps ESTM50, anticorps regulator of G protein signaling 4, anticorps regulator of G-protein signaling 4, anticorps RGS4, anticorps Rgs4

Sujet: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein negatively regulates signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37 % identical to RGS1 and 97 % identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.
Alias Symbols: MGC2124, MGC60244, RGP4, SCZD9
Protein Interaction Partner: GABBR1, KRIT1, PLCB1, COPB2, GNAQ, COPB1, ERBB3, PTAFR, GNAI2, GNAO1, GNAI1, CALM1, GNAI3, GNAT1,
Protein Size: 205

Poids moléculaire: 23 kDa

ID gène: 5999

NCBI Accession: NM_005613, NP_005604

UniProt: P49798

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling