Amphiregulin anticorps (Middle Region)

N° du produit ABIN2779308

Cet anticorps Lapin Polyclonal détecte spécifiquement Amphiregulin dans WB. Il présente une réactivité envers Humain, Boeuf (Vache), Cheval, Porc, Chien et Mouton.

Aperçu rapide pour Amphiregulin anticorps (Middle Region) (ABIN2779308)

Antigène: Amphiregulin (AREG)

Reactivité: Humain, Boeuf (Vache), Cheval, Porc, Chien, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Amphiregulin est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Amphiregulin anticorps

Épitope: Middle Region

Séquence: PQIPGYIVDD SVRVEQVVKP PQNKTESENT SDKPKRKKKG GKNGKNRRNR

Homologie: Cow: 91%, Dog: 91%, Horse: 91%, Human: 100%, Pig: 91%, Sheep: 91%

Attributs du produit: This is a rabbit polyclonal antibody against AREG. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human AREG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 252 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Amphiregulin

Antigène: Amphiregulin (AREG)

Autre désignation: AREG

Sujet: The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This encoded protein is associated with a psoriasis-like skin phenotype.
Alias Symbols: AR, AREGB, CRDGF, MGC13647, SDGF
Protein Interaction Partner: KRTAP10-3, WDR92, UBC, APP, UBQLN4, WT1, EGFR, CCND3, MMP9,
Protein Size: 252

Poids moléculaire: 28 kDa

ID gène: 374

NCBI Accession: NM_001657, NP_001648

UniProt: P15514

Pathways: Signalisation RTK, EGFR Signaling Pathway