CDK2 anticorps (Middle Region)

N° du produit ABIN2779325

Détail du produit anti-CDK2 anticorps

Antigène: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Mouton, Poisson zèbre (Danio rerio), Chévre, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: VLHRDLKPQN LLINTEGAIK LADFGLARAF GVPVRTYTHE VVTLWYRAPE

Homologie: Cow: 100%, Goat: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CDK2. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 298 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CDK2 (ABIN2779325)

Huang, Chen, Wu, Huang, He, Tang, Wang, Wang: "The zebrafish miR-462/miR-731 cluster is induced under hypoxic stress via hypoxia-inducible factor 1α and functions in cellular adaptations." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 12, pp. 4901-13, (2015) (PubMed).

Détails sur CDK2

Antigène: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Autre désignation: CDK2 (CDK2 Produits)

Synonymes: anticorps p33(CDK2), anticorps A630093N05Rik, anticorps wu:fa10c02, anticorps zgc:56598, anticorps zgc:77684, anticorps eg1, anticorps CDKN2, anticorps cdk2L, anticorps cyclin dependent kinase 2, anticorps cyclin-dependent kinase 2, anticorps cyclin-dependent kinase 2 S homeolog, anticorps CDK2, anticorps Cdk2, anticorps cdk2, anticorps cdk2.S

Sujet: Phospho-cdk2 (Thr160) probably involved in the control of the cell cycle. It interacts with cyclins A, D, or E. Activity of cdk2 is maximal during S phase and G2.
Alias Symbols: p33(CDK2)
Protein Interaction Partner: MAPT, CDKN1A, CCNA2, VCP, SAMHD1, IMPDH2, CDK2, SKP1, FZR1, CKS2, CKS1B, CCNE2, GOLGA2, CREBBP, CDKN1C, CDKN1B, CCNE1, CDK13, SKP2, RBL2, RBL1, CCNB1, COPS5, PTMA, HIST1H1A, PRDX1, CCNJ, CDK7, CDK3, EP300, ATP1A1, MYBL2, MNAT1, HSPD1, HSP90AB1, HSP90AA1,
Protein Size: 298

Poids moléculaire: 34 kDa

ID gène: 1017

NCBI Accession: NM_001798, NP_001789

UniProt: P24941

Pathways: Signalisation PI3K-Akt, Cycle Cellulaire, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA