ILK anticorps (C-Term)

N° du produit ABIN2779334

L’anticorps Lapin Polyclonal anti-ILK a été validé pour WB. Il convient pour détecter ILK dans des échantillons de Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chien, Boeuf (Vache), Chévre, Cobaye, Cheval, Lapin et Mouton.

Aperçu rapide pour ILK anticorps (C-Term) (ABIN2779334)

Antigène: ILK (Integrin-Linked Kinase (ILK))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chien, Boeuf (Vache), Chévre, Cobaye, Cheval, Lapin, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ILK est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ILK anticorps

Épitope: C-Term

Séquence: MKVALEGLRP TIPPGISPHV CKLMKICMNE DPAKRPKFDM IVPILEKMQD

Homologie: Cow: 100%, Dog: 100%, Goat: 82%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ILK. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ILK

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ILK

Antigène: ILK (Integrin-Linked Kinase (ILK))

Autre désignation: ILK

Sujet: Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Alias Symbols: ILK-2, P59
Protein Interaction Partner: UBC, TRIM27, PARVG, PARVA, RICTOR, ITGB1, MTOR, AKT1, FKBP5, HSPH1, FAF1, CARM1, UGP2, PPAT, FBXO6, ACACA, LIMS2, RHOT1, FANCI, ATAD3A, HEATR1, CLN6, TRAFD1, ZNF568, TIMM50, RHOT2, TRABD, LPCAT1, VKORC1, RPL13, ABCE1, RBBP7, RAF1, SDF4, SEC61A1, PARVB, AK
Protein Size: 452

Poids moléculaire: 49 kDa

ID gène: 3611

NCBI Accession: NM_004517, NP_004508

UniProt: Q13418

Pathways: Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration