beta Arrestin 1 anticorps (Middle Region)
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- Antigène Voir toutes beta Arrestin 1 (ARRB1) Anticorps
- beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))
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Épitope
- Middle Region
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Reactivité
- Humain, Boeuf (Vache), Cheval, Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp beta Arrestin 1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- NETPVDTNLI ELDTNDDDIV FEDFARQRLK GMKDDKEEEE DGTGSPQLNN
- Homologie
- Cow: 90%, Dog: 100%, Horse: 100%, Human: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against ARRB1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human ARRB1
- Top Product
- Discover our top product ARRB1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 418 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))
- Autre désignation
- ARRB1 (ARRB1 Produits)
- Synonymes
- anticorps arrb1, anticorps MGC83787, anticorps arb1, anticorps arr1, anticorps barr1, anticorps betaarr1, anticorps 1200006I17Rik, anticorps AW208571, anticorps G430100A01Rik, anticorps ARB1, anticorps ARR1, anticorps BARRES, anticorps arrestin beta 1, anticorps arrestin, beta 1, anticorps arrestin beta 1 L homeolog, anticorps beta-arrestin 1, anticorps putative beta-arrestin 1, anticorps ARRB1, anticorps arrb1, anticorps arrb1.L, anticorps CpipJ_CPIJ016988, anticorps CpipJ_CPIJ017114, anticorps Smp_122900, anticorps Smp_126080, anticorps Smp_176980, anticorps Smp_152290, anticorps Arrb1
- Sujet
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Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described, however, their exact functions are not known.
Alias Symbols: ARB1, ARR1
Protein Interaction Partner: MAPK9, UBC, PTGER4, SRC, GNMT, NOTCH1, ARRDC1, PTAFR, MAP2K3, LIMK1, PDXP, MAPK14, CLTC, CFL1, AP2A1, MAP3K5, AKT1, AGTR1, MAP2K4, MAPK10, CSK, EDNRA, Agtr1a, NEK6, PIK3R2, NFKBIA, AXIN1, YY1, BTK, BAG1, ADRB1, ADH6, RPL15, PDE4D, Mlnr, Trhr, ARRDC4, ARRD
Protein Size: 418 - Poids moléculaire
- 47 kDa
- ID gène
- 408
- NCBI Accession
- NM_004041, NP_004032
- UniProt
- P49407
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Nuclear Hormone Receptor Binding, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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