MAP3K8 anticorps (N-Term)

N° du produit ABIN2779366

Détail du produit anti-MAP3K8 anticorps

Antigène: MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8))

Épitope: N-Term

Reactivité: Humain, Souris, Boeuf (Vache), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP3K8 est non-conjugé

Application: Western Blotting (WB)

Séquence: ASEEPAVYEP SLMTMCQDSN QNDERSKSLL LSGQEVPWLS SVRYGTVEDL

Homologie: Cow: 75%, Horse: 87%, Human: 100%, Mouse: 85%

Attributs du produit: This is a rabbit polyclonal antibody against MAP3K8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MAP3K8

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 467 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MAP3K8

Antigène: MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8))

Autre désignation: MAP3K8 (MAP3K8 Produits)

Synonymes: anticorps MAP3K8, anticorps COT, anticorps EST, anticorps ESTF, anticorps MEKK8, anticorps TPL2, anticorps Tpl-2, anticorps c-COT, anticorps Cot, anticorps Cot/Tpl2, anticorps Est, anticorps Estf, anticorps Tpl2, anticorps D17TPL2, anticorps mitogen-activated protein kinase kinase kinase 8, anticorps MAP3K8, anticorps map3k8, anticorps Map3k8

Sujet: MAP3K8 is a member of the serine/threonine protein kinase family. This kinase can activate both the MAP kinase and JNK kinase pathways. This kinase was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This kinase was
Alias Symbols: COT, EST, ESTF, FLJ10486, TPL2, Tpl-2, c-COT, MEKK8
Protein Interaction Partner: RELA, MAP2K1, RIPK1, NFKB1, ACY3, STIP1, HSP90AA1, TAB2, TRAF6, TRAF2, CD40, TNIP2, Nedd4, MAP3K14, MAP2K4, BMPR2, CHUK, REL, AKT1, NFKB2, KSR2,
Protein Size: 467

Poids moléculaire: 53 kDa

ID gène: 1326

NCBI Accession: NM_005204, NP_005195

UniProt: P41279

Pathways: Signalisation PI3K-Akt, TCR Signaling