CXCR4 anticorps (N-Term)

N° du produit ABIN2779387

Détail du produit anti-CXCR4 anticorps

Antigène: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Épitope: N-Term

Reactivité: Humain, Souris, Lapin, Porc, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCR4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Séquence: MEGISIYTSD NYTEEMGSGD YDSMKEPCFR EENANFNKIF LPTIYSIIFL

Homologie: Horse: 89%, Human: 91%, Mouse: 77%, Pig: 91%, Rabbit: 85%, Rat: 77%

Attributs du produit: This is a rabbit polyclonal antibody against CXCR4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CXCR4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 352 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CXCR4

Antigène: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Autre désignation: CXCR4 (CXCR4 Produits)

Synonymes: anticorps CD184, anticorps D2S201E, anticorps FB22, anticorps HM89, anticorps HSY3RR, anticorps LAP3, anticorps LCR1, anticorps LESTR, anticorps NPY3R, anticorps NPYR, anticorps NPYRL, anticorps NPYY3R, anticorps WHIM, anticorps Cmkar4, anticorps PB-CKR, anticorps PBSF/SDF-1, anticorps Sdf1r, anticorps CXC-R4-B, anticorps CXCR-4-B, anticorps cd184, anticorps cxcr4, anticorps fb22, anticorps hm89, anticorps hsy3rr, anticorps lap3, anticorps lcr1, anticorps lestr, anticorps npy3r, anticorps npyr, anticorps npyrl, anticorps npyy3r, anticorps xcxcr4, anticorps CXC-R4, anticorps CXCR-4, anticorps d2s201e, anticorps whim, anticorps CXC-R4-A, anticorps CXCR-4-A, anticorps xCXCR4, anticorps CXCR4, anticorps cb403, anticorps zgc:109863, anticorps cb824, anticorps C-X-C motif chemokine receptor 4, anticorps chemokine (C-X-C motif) receptor 4, anticorps C-X-C motif chemokine receptor 4 S homeolog, anticorps C-X-C chemokine receptor type 4, anticorps C-X-C motif chemokine receptor 4 L homeolog, anticorps chemokine (C-X-C motif), receptor 4b, anticorps chemokine (C-X-C motif) receptor 4a, anticorps CXCR4, anticorps Cxcr4, anticorps cxcr4.S, anticorps cxcr4, anticorps LOC100049444, anticorps cxcr4.L, anticorps cxcr4b, anticorps cxcr4a

Sujet: CXCR4 is a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM
Protein Interaction Partner: UBC, ITCH, nef, P4HB, CD4, env, MYBL2, ST13, ATP13A2, CXCL12, PTPN11, STAM, CAV1, SUMO4, HLA-C, SDC4, HSPA8, GNA13, STAT5B, SOCS3, SOCS1, CCR5, PTK2, STAT2, STAT1, JAK3, DPP4, PTPN6, VAV1, CXCR4, MYH9, PTPRC, JAK2, JAK1, GNAI1, ELANE, CTSG, ADRBK2, ARRB2,
Protein Size: 352

Poids moléculaire: 40 kDa

ID gène: 7852

NCBI Accession: NM_003467, NP_003458

UniProt: P61073

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events